- Original Article
- Polymorphisms of interleukin-1β promoter in simple febrile seizures
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Jang Won Yoon, Eun Jung Choen, Young Hyuk Lee
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Clin Exp Pediatr. 2008;51(9):1007-1011. Published online September 15, 2008
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Purpose : Febrile seizure (FS) is the most common type of seizure. The role of genetic factors in FSs has long been recognized. A positive family history can be elicited in 25-40% of patients with FSs; nonetheless, the genes responsible for FSs in the majority of the population remain unknown. Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that acts as an... |
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- Unprovoked seizures in children with complex febrile convulsion; short-term outcome
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Ji Yeon Choi, Eun Jung Cheon, Young Hyuk Lee
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Clin Exp Pediatr. 2007;50(8):757-760. Published online August 15, 2007
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Purpose : Febrile convulsions (FC) were considered to be a benign seizure syndrome that is distinct from epilepsy. But it is thought that children with complex features i.e., partial or prolonged seizures or multiple episodes of FC would bear a higher risk of developing unprovoked seizures. The aim of this study is to look into the relative significance of each... |
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- A clinical study of child bacterial meningitis in Daejeon and Chungcheong area : 2001-2005
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Yong Joo Lee, Soo Jin Lee, Ho Jin Park, Young Hyuk Lee, So Young Kang, Young Chang Kim, In Kyu Lee, Kyung Yeon Lee, Keon Su Lee, Won Seop Kim
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Clin Exp Pediatr. 2007;50(2):157-162. Published online February 15, 2007
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Purpose : The purpose of this study was to analyze the epidemiology, causative organism, clinical manifestation and prognosis of bacterial meningitis for children after the introduction of Haemophilus influenzae type b (Hib) vaccine in Daejeon and Chungcheong area.
Methods : We analyzed retrospectively 53 medical records who had been diagnosed with bacterial meningitis at 10 general or university hospitals... |
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- Correlation of inhalant MAST on chronically coughing children
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Jung Min Yun, Eui Jung Roh, Jae Woo Lim, Eun Jung Choen, Kyoung Og Ko, Young Hyuk Lee
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Clin Exp Pediatr. 2006;49(6):643-647. Published online June 15, 2006
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Purpose : Recently, incidences of chronic cough with allergic disease have been increased. The identification of specific allergens for chronically coughing children is significant for diagnosis, proper treatment and prevention. The aim of this study was to identify significant contributors for sensitization in chronically coughing children.
Methods : A total of 106 children, aged 1-6 years, visiting for chronic cough(>3 weeks),... |
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- Detection of Enterovirus in Patients with Aseptic Meningitis by Reverse Transcription and Polymerase Chain Reaction
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Souck Joong Yoon, Sung Jin Hong, Young Hyuk Lee, Min Hee Kim, Kyo Sun Kim, Kyu Hyun Park, Jae Myun Lee, Won Young Lee
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Clin Exp Pediatr. 1994;37(9):1226-1234. Published online September 15, 1994
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The aim of this study was to determine the applicability of reverse transcription and polymerase chain reaction(RT/PCR) for routine diagnostic use and for the detection of enteroviral mentigitis, Primers were selected in the highly conserved part of the 5'-non-coding region of the enteroviral genome. Enteroviral RNA was detected by the RT/PCR in routinely collected cerebrospinal fluids(CSF) of patients with aseptic... |
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- The Comparision of Brain Computed Tomography and Isotope Cisternography in Communicating Hydrocephalus
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Jong Chan Kim, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Chul Hu, Soon Ki Hong, Young Hyuk Lee
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Clin Exp Pediatr. 1992;35(1):9-16. Published online January 15, 1992
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Brain computed tomograpy is particularly accurate in defining cerebrospinal fluid (CSF) space because of the relatively great density difference between CSF and brain parenchyma. This noninvasive procedure has very quickly become definitive in the diagnosis of hydrocephalus. However, while the typical clinical and radiological picture of a hydrocephalic patient leaves no doubt as to the need for adequate surgical treatment.... |
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- A case of double compartment hydrocephalus.
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Eun Kyung Oh, Hae Young Lee, Jae Seung Yang, Chul Hu, Young Hyuk Lee
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Clin Exp Pediatr. 1991;34(9):1305-1310. Published online September 30, 1991
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The double compartment hydrocephalus is now recognized as a clinical entity needing early
diagnosis and treatment. By definition, the concept of double compartment hydrocephalus indicates
seperate and individually progressing, usually sequential, hydrocephalus of the supratentorial and
infratentorial CSF ventricles. In most instances, this entity consists of supratentorial hydrocephalus
of the third and lateral ventricles (as a result of aqueductal stenosis) that has been treated... |
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- A case of atypical neurofibromatosis type 1.
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Eun Joo Choi, Young Hyuk Lee, Min Hee Kim, Kyo Sun Kim
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Clin Exp Pediatr. 1991;34(7):1034-1039. Published online July 31, 1991
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Almost of all patients with neurofibromatosis type I show caf6-au-lait macules on their skin.
These macules are thought to be early sign of neurofibromatosis in childhood.
We experienced a case of neurofibromatosis type I in a 10-year-old-boy who did not have
caf6-au-lait macules, but progressive psychomotor retardation, short attention span, hyperactivity
and megalencephaly. The brain C-T findings showed diffuse cerebromalacia and ventriculomegaly.
We confirmed the... |
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- Clinical significance of mega cisterna magna.
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Young Hyuk Lee, Min Hee Kim, Kyo Sun Kim, Hae Jeong Jeon, Jeong Hee Park
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Clin Exp Pediatr. 1991;34(7):971-977. Published online July 31, 1991
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The mega cistema magna is a congenital developmental malformation. The size of the cistema
magna and the criterion of the mega cistema is still debatable. A clinical study had been performed
on 12 children with mega cistema magna diagnosed by computed tomography scan from January 1980
to December 1990.
The results are summarized as follows:
1) Among 4900 consecutive unselected computed tomography scans, twelve cases with... |
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- A case of myelofibrosis with juvenile xanthogranuloma.
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Jong Chan Kim, Hae Yong Lee, Hwang Min Kim, Baek Keun Lim, Jong Soo Kim, Young Hyuk Lee
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Clin Exp Pediatr. 1991;34(6):869-876. Published online June 30, 1991
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Myelofibrrosis is characterized by anemia, leukoerythroblastosis, extramedullary hematopoiesis,
hepatosplenomegaly, osteosclerosis and fibrosis of bone marrow. Idiopathc myelofibrosis is usually a
disease of the adult and is rare in the pediatric age group. Juvenile xanthogranuloma is characterized
by multiple papules on forehead and scalp. Lipid laden histiocytes and Touton giant cell are found in
skin biopsy. We experienced a case of myelofibrosis with juvenile xanthogranuloma.... |
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- A study on the length of the human umbilical cord.
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Min Hee Kim, Young Hyuk Lee, Kyo Sun Kim
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Clin Exp Pediatr. 1991;34(12):1641-1646. Published online December 31, 1991
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A short umbilical cord is defined as 35 cm or less, whereas a long cord is 80 cm or more.
Short umbilical cords have been associated with a delay in the second stage of labor, irregular fetal
heart tones, placental abruption, rupture of the umbilical cord, inversion of the uterus, birth asphyxia,
umbilical hernia and long umbilical cord have been associated more frequently... |
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- Comparative Study of the Abilities of Visual Motor Integration in Korea Children to That of Berry's Results.
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Chang Jun Coe, Young Hyuk Lee
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Clin Exp Pediatr. 1989;32(2):191-197. Published online February 28, 1989
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Visual.Motor Integration (VMI) test, designed by Beery, is one of the battery, which is commomly
used in investigating the developmental status of child. As the test was designed for American
children, the test may be not feasible for Korean children because of difference of cultural back.
ground, race as well as econornic status.
1674 normal Korean children aged from 5 to 12 were tested... |
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- Clinical Evaluation of the Arachnoid Cysts in the Pediatric Age Group.
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Ho Taek Kim, Young Hyuk Lee, Chang Jun Coe
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Clin Exp Pediatr. 1988;31(4):467-473. Published online April 30, 1988
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Arachnoid cysts are benign cysts occuring in the cerebrospinal axis in relation to the arachnoid
membrane.
From Jan, 1974 unitl June, 1986. we evaluated the clinical features and outcome of the arachnoid
cyst by the review of the medical records and followup study of 20 cases in pediatric age group, and
the results are as follows:
1) The age distribution of the patients was from 2... |
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- Visual Motor Integration Abilities of Children with Learning Disorders.
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Chang Jun Coe, Young Hyuk Lee, Jung Keun Kim
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Clin Exp Pediatr. 1988;31(3):339-347. Published online March 31, 1988
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Children with learning problems are known to a social, educational as well as neurological
problems.
Learning disorder is usually defined as following children with normal intelligence and without
serious psychological problems experiencing serious degree of difficulty to acquire a proper skill to
learn, reading, writing and calculation.
These children are usually hyperactive, easily distractable, may manifests defect in visual motor
integration and various soft neurologic signs.
As... |
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- A Case of Infantile Cortical Hyperostosis.
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Jae Kyoun Rhim, Young Hyuk Lee, Chang Jun Coe, Duk Jin Yoon
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Clin Exp Pediatr. 1988;31(11):1494-1498. Published online November 30, 1988
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Recently we have experienced a case of infantile cortical hyperostosis. The patients was 2 months
old male who complained irritability, soft tissue swelling of both lower extremities. X-ray showed
periosteal new bone formation on both tibiae. Bone scan revealed hot uptake at the lesion.
We are reporting this infantile cortical hyperostosis with reviewing literatures. |
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- A Clinical Assessment of Children with Learning Disables.
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Cang Jun Coe, Young Hyuk Lee, Jung Keun Kim, In Suck Ryu
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Clin Exp Pediatr. 1987;30(10):1078-1091. Published online October 31, 1987
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Clinical investigation and assessment has been performed on 201 children with various learning
disables, who are studying at special classes from 6 different school in Seoul. By this clinical study
including medical examination following results were obtained.
1) Their age ranged from 7 to 13 year and male was dominant in number rating 1.3:1.
2) Their intelligence has been assessed by Korean-WISC test, and the score... |
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- Clinical Study of Therapeutic Effect in Status Epilepticus.
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Young Hyuk Lee, Chang Jun Coe
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Clin Exp Pediatr. 1986;29(1):72-78. Published online January 31, 1986
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A clinical studies were conducted to determine the effectiveness of anticonvulsant treatment in 90 cases of status epilepticus in children who had been admitted to Pediatric Department of Yonsei University Medical Center from January 1979 to July 1984. The results were obtained as follows:
1) The incidence was 9.9% of epileptics who visit to our clinic at the same period of time.
2) In... |
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